Maximum penalized likelihood estimation in a gamma-frailty model.


The shared frailty models allow for unobserved heterogeneity or for statistical dependence between observed survival data. The most commonly used estimation procedure in frailty models is the EM algorithm, but this approach yields a discrete estimator of the distribution and consequently does not allow direct estimation of the hazard function. We show how… (More)

5 Figures and Tables


  • Presentations referencing similar topics