Maximum Likelihood Estimation of T 1 Relaxation Parameters Using VARPRO

  title={Maximum Likelihood Estimation of T 1 Relaxation Parameters Using VARPRO},
  author={Justin P. Haldar and J. G. Anderson and S Sun},
INTRODUCTION Accurate T1 relaxation time parameter estimation is essential for a wide variety of quantitative MR applications; for example, obtaining accurate T1 values can be crucial in problems such as quantitative contrast enhanced imaging studies, image segmentation and tissue characterization, and absolute metabolite quantification in NMR spectroscopy. Typical experiments designed specifically for T1 estimation often involve acquiring multiple datasets, with the timings within the… CONTINUE READING


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