Maximizing the retention of antigen specific lymphocyte function after cryopreservation.

@article{Disis2006MaximizingTR,
  title={Maximizing the retention of antigen specific lymphocyte function after cryopreservation.},
  author={Mary Lenora Disis and Corazon dela Rosa and Vivian Goodell and Ling-Yu Kuan and Jennie C C Chang and Kristina Kuus-Reichel and Timothy M. Clay and H Kim Lyerly and Sonny Bhatia and Smita A. Ghanekar and Vernon C. Maino and Holden T. Maecker},
  journal={Journal of immunological methods},
  year={2006},
  volume={308 1-2},
  pages={13-8}
}
The ability to cryopreserve lymphocytes in peripheral blood mononuclear cells (PBMC) to retain their function after thawing is critical to the analysis of cancer immunotherapy studies. We evaluated a variety of cryopreservation strategies with the aim of developing an optimized protocol for freezing and thawing PBMC to retain viability and function. We… CONTINUE READING