Maximizing the impact of antimicrobial stewardship: the role of diagnostics, national and international efforts

  title={Maximizing the impact of antimicrobial stewardship: the role of diagnostics, national and international efforts},
  author={Deirdre O'Brien and Ian Malcolm Gould},
  journal={Current Opinion in Infectious Diseases},
Purpose of review The decline in the development and approval of new antimicrobial agents, especially those with activity against multidrug-resistant Gram-negative bacteria, has arisen as one of the major public health threats of the 21st century. Antimicrobial stewardship has emerged as a key available means to attenuate this threat. Because of the immediacy of the crisis imposed by the dearth of new antimicrobial agents, this review aims to seek out innovative mechanisms that could complement… 
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Integrating rapid pathogen identification and antimicrobial stewardship significantly decreases hospital costs.
CONTEXT Early diagnosis of gram-negative bloodstream infections, prompt identification of the infecting organism, and appropriate antibiotic therapy improve patient care outcomes and decrease health
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  • N. Fishman
  • Medicine
    Infection Control & Hospital Epidemiology
  • 2012
Recommendations for the mandatory implementation of antimicrobial stewardship throughout health care are outlined, process and outcome measures to monitor these interventions are suggested, and deficiencies in education and research in this field are addressed as well as the lack of accurate data on antimicrobial use in the United States.
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  • 2013
Hospitals evaluating rapid MRSA tests should weigh factors such as their relative costs, reliability, and sample-processing times, as well as the need for policies and processes to ensure the prompt communication of test results to clinicians.
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    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
  • 2008
The aim of antimicrobial management or stewardship programmes is to ensure proper use of antimacterial agents in order to provide the best treatment outcomes, to lessen the risk of adverse effects, and to promote cost-effectiveness.
The Chennai Declaration: a solution to the antimicrobial resistance problem in the Indian subcontinent.
  • A. Ghafur
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