Mature adipocytes in bone marrow protect myeloma cells against chemotherapy through autophagy activation

Abstract

A major problem in patients with multiple myeloma is chemotherapy resistance, which develops in myeloma cells upon interaction with bone marrow stromal cells. However, few studies have determined the role of bone marrow adipocytes, a major component of stromal cells in the bone marrow, in myeloma chemotherapy resistance. We reveal that mature human… (More)
DOI: 10.18632/oncotarget.6020

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