Mature B-cell acute lymphoblastic leukemia with t(9;11) translocation: a distinct subset of B-cell acute lymphoblastic leukemia

@article{Tsao2004MatureBA,
  title={Mature B-cell acute lymphoblastic leukemia with t(9;11) translocation: a distinct subset of B-cell acute lymphoblastic leukemia},
  author={Lawrence Tsao and Hediya Y Draoua and Ifeyinwa Osunkwo and Subhadra V. Nandula and V. V. S. Murty and Mahesh M. Mansukhani and Govind Bhagat and Bachir Alobeid},
  journal={Modern Pathology},
  year={2004},
  volume={17},
  pages={832-839}
}
Mature B-cell acute lymphoblastic leukemia (ALL) is typically associated with the FAB-L3 morphology and rearrangement of the MYC gene, features characteristic of the leukemic phase of Burkitt's lymphoma. However, the term ‘mature’ has also been used to describe other rare cases of B-ALL with light-chain surface immunoglobulin expression. In contrast, infantile B-cell ALL is generally characterized by rearrangement of the MLL gene, an immature pro-B-cell phenotype, and CD10 negativity. We… CONTINUE READING