Maturational and maintenance effects of testosterone on terminal axon density and neuropeptide expression in the rat vas deferens

@article{Keast2002MaturationalAM,
  title={Maturational and maintenance effects of testosterone on terminal axon density and neuropeptide expression in the rat vas deferens},
  author={J. Keast and R. Gleeson and A. Shulkes and M. Morris},
  journal={Neuroscience},
  year={2002},
  volume={112},
  pages={391-398}
}
Testosterone causes growth of many pelvic ganglion cells at puberty and their maintenance during adulthood. Here we have focused on two populations of pelvic ganglion cells that project to the rat vas deferens: noradrenergic neurons that innervate the smooth muscle and synthesize neuropeptide Y, and cholinergic neurons that primarily innervate the mucosa and contain vasoactive intestinal peptide. We have assessed the muscle innervation after pre- or postpubertal castration, using… Expand
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  • Biology, Medicine
  • International review of cytology
  • 2006
TLDR
Advances in this area will come from a better understanding of the effects of injury on the cellular signaling process in pelvic neurons and also the role of neurotrophic factors during development, maintenance, and repair of these axons. Expand
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