Maturation of spontaneous and agonist-induced uterine contractions in the peripartum mouse uterus.

@article{Mackler1999MaturationOS,
  title={Maturation of spontaneous and agonist-induced uterine contractions in the peripartum mouse uterus.},
  author={Ari M Mackler and Charles A. Ducsay and Johannes D. Veldhuis and Steven M. Yellon},
  journal={Biology of reproduction},
  year={1999},
  volume={61 4},
  pages={873-8}
}
This study tested the hypothesis that the uterus achieves maximum contractile capabilities before the onset of labor. Basal and agonist-stimulated contractions were assessed in uterine strips on Day 15 or 18 of pregnancy, the day of parturition, or 1 day postpartum (n = 4-13 per group). Spontaneous contractions were evident in all groups (n = 4-13 per gestational group); contraction frequency was greater in peripartum groups than in virgin controls ( approximately 4.6 versus 2.8/200 sec). Peak… CONTINUE READING