Maturation of neuromuscular transmission during early development in zebrafish.

@article{Nguyen1999MaturationON,
  title={Maturation of neuromuscular transmission during early development in zebrafish.},
  author={Peter V. Nguyen and Laurent Aniksztejn and Stefano Catarsi and Pierre Drapeau},
  journal={Journal of neurophysiology},
  year={1999},
  volume={81 6},
  pages={
          2852-61
        }
}
We have examined the rapid development of synaptic transmission at the neuromuscular junction (NMJ) in zebrafish embryos and larvae by patch-clamp recording of spontaneous miniature endplate currents (mEPCs) and single acetylcholine receptor (AChR) channels. Embryonic (24-36 h) mEPCs recorded in vivo were small in amplitude (<50 pA). The rate of mEPCs increased in larvae (3.5-fold increase measured by 6 days), and these mEPCs were mostly of larger amplitude (10-fold on average) with (</=5-fold… 
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