Maturation of function in dendritic cells for tolerance and immunity.

  title={Maturation of function in dendritic cells for tolerance and immunity.},
  author={B. J. C. Quah and Helen C O'Neill},
  journal={Journal of cellular and molecular medicine},
  volume={9 3},
The capacity of antigen presenting dendritic cells (DC) to function in both tolerance and immunity is now well documented. The function and characteristics of different DC subsets are reviewed here and their capacity to activate T cells under different conditions of maturation and activation is discussed. The immunogenic potential of exosomes produced by DC is also considered in light of evidence that the capacity of exosomes to activate T cells for tolerance or immunity appears to mirror that… CONTINUE READING
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