Maturation in vitro of human oocytes from unstimulated cycles: selection of the optimal day for ovum retrieval based on follicular size.

@article{Cobo1999MaturationIV,
  title={Maturation in vitro of human oocytes from unstimulated cycles: selection of the optimal day for ovum retrieval based on follicular size.},
  author={Ana Cristina Cobo and Antonio Requena and Fernando Neuspiller and M Aragon s and Amparo Mercader and Jos{\'e} Navarro and Carlos Sim{\'o}n and Jose Alejandro Remohi and Antonio Pellicer},
  journal={Human reproduction},
  year={1999},
  volume={14 7},
  pages={
          1864-8
        }
}
The potential use of immature oocytes for in-vitro fertilization (IVF) requires the conditions for successful maturation to be defined. This study focused on the day of oocyte retrieval. The selection of a dominant follicle may induce endocrine changes in the remaining cohort that may be detrimental to their subsequent fertilization and embryonic development. Natural cycles in volunteer donors were followed by measurement of serum oestradiol and by vaginal ultrasound, starting on day 3 of the… Expand
Selection of the optimal day for oocyte retrieval based on the diameter of the dominant follicle in hCG-primed in vitro maturation cycles.
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The results suggest that oocyte collection in IVM cycles should be performed when the DF is 14 mm diameter or less, and that Sibling immature oocytes may be affected detrimentally if a DF >14 mm is present at oocytes collection. Expand
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Optimization of clinical management of IVM cycles will enhance pregnancy outcome, so that IVM might become an effective alternative assisted reproduction treatment for infertile patients irrespective of the cause of infertility. Expand
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Pregnancy rates after IVM correlate with the number of immature oocytes retrieved, and this is best predicted by an ultrasonographic assessment of the AFC. Expand
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Immature oocyte retrieval combined with IVM could possibly replace standard stimulated IVF in selected patients and replace standard stimulation in healthy regularly cycling women referred for IVF (ICSI) due to severe male infertility. Expand
Strategies in human in-vitro maturation and their clinical outcome.
  • A. Mikkelsen
  • Medicine, Biology
  • Reproductive biomedicine online
  • 2005
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It is suggested that in future, immature oocyte retrieval combined with IVM could replace conventional IVF in selected patients. Expand
In-vitro maturation of oocytes from unstimulated polycystic ovaries.
TLDR
The indications for in-vitro maturation (IVM) of immature oocytes would include women requiring IVF who have PCO, those with primarily poor quality embryos in repeated previous IVF cycles for no apparent reason, poor responders to high dose gonadotrophin stimulation for IVF, and finally, women with PCO who are considering egg donation. Expand
Immature oocyte in-vitro maturation: clinical aspects.
TLDR
Optimization of clinical management of IVM cycles will enhance pregnancy outcome, so that IVM might become an effective alternative assisted reproduction treatment for infertile patients irrespective of the cause of infertility. Expand
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It is suggested that in vitro maturation of immature oocytes from unstimulated ovaries with mature follicular fluid could be used successfully in a donor oocyte program after in vitro fertilization. Expand
Pregnancy after transfer of embryos which were generated from in-vitro matured oocytes.
In-vitro maturation of human oocytes is an important technique in assisted reproduction due to its potential for reducing the use of fertility drugs. We offered this technique as an alternative toExpand
Fertilization and developmental competence of bovine oocytes derived from different categories of antral follicles
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It is concluded that blastocysts from follicles ranging from >2 to 8 mm in size have a similar developmental potential and oocytes from 1‐ to 2‐mm follicles have a significantly lower competence to undergo in vitro maturation and fertilization and, under the conditions of the authors' experiments, completely lack the capability to cleave beyond the 8‐cell stage. Expand
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Oocytes of varying stages of maturity were aspirated from follicles primed with either human menopausal gonadotropin (hMG) and human chorionic gonadotropic hormone (hCG) or a combination of follicle-stimulating hormone (FSH), hMG and hCG and eight pregnancies were established. Expand
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Investigating the effect of size of from which goat oocytes originate on their subsequent ability to be fertilized and to undergo early embryonic development in vitro found no significant difference in the cleavage rate after insemination. Expand
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TLDR
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Maturation in vitro of immature human oocytes for clinical use.
Human oocyte maturation is considered as the reinitiation and completion of the first meiotic division from the germinal vesicle stage (prophase I) to metaphase II, and the accompanying cytoplasmicExpand
Current status of IVM/IVF and embryo culture in humans and farm animals
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A further improvement in the rate of development to blastocysts and cell number was achieved by culture in simple SOF medium with amino acids and 8 mg/ml BSA, demonstrating that bovine embryos can be produced very successfully in simple culture medium without any supportive cocultured cells. Expand
Commercial aspects of oocyte retrieval and in vitro fertilization (IVF) for embryo production in problem cows
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Ultrasound-guided follicular aspiration and IVF was successful in producing pregnancies from previously non-productive problem donors and in vitro embryo production techniques were employed. Expand
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TLDR
The developmental capability of primary oocytes is higher in regular cycling women than in irregular cycling and anovulatory women with polycystic ovary disease. Expand
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