Maturation and migration of murine CD4 single positive thymocytes and thymic emigrants

@inproceedings{Xu2014MaturationAM,
  title={Maturation and migration of murine CD4 single positive thymocytes and thymic emigrants},
  author={Xi Xu and Qing Ge},
  booktitle={Computational and structural biotechnology journal},
  year={2014}
}
T lymphopoiesis in the thymus was thought to be completed once they reach the single positive (SP) stage, when they are "fully mature" and wait to be exported at random or follow a "first in-first out" manner. Recently, accumulating evidence has revealed that newly generated SP thymocytes undergo further maturation in the thymic medulla before they follow a… CONTINUE READING