Matrix remodeling in the ovary: regulation and functional role of the plasminogen activator and matrix metalloproteinase systems.

@article{Ny2002MatrixRI,
  title={Matrix remodeling in the ovary: regulation and functional role of the plasminogen activator and matrix metalloproteinase systems.},
  author={Tor Ny and Patrik Wahlberg and Ida J M Br{\"a}ndstr{\"o}m},
  journal={Molecular and cellular endocrinology},
  year={2002},
  volume={187 1-2},
  pages={29-38}
}
In each reproductive cycle, extensive tissue remodeling takes place in the ovary during follicular development, ovulation, formation and regression of corpus luteum (CL) and follicular atresia. Several lines of indirect evidence suggest that these changes are mediated, in part, by proteases belonging to the plasminogen activator (PA) and the matrix metalloproteinase (MMP) systems. These two enzyme systems include both proteinases and associated inhibitors, that are thought to act in concert via… CONTINUE READING
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