Matrix remodeling after stroke. De novo expression of matrix proteins and integrin receptors.

@article{Ellison1999MatrixRA,
  title={Matrix remodeling after stroke. De novo expression of matrix proteins and integrin receptors.},
  author={Julie A. Ellison and Frank Barone and Giora G Z Feuerstein},
  journal={Annals of the New York Academy of Sciences},
  year={1999},
  volume={890},
  pages={204-22}
}
Following an ischemic insult to the central nervous system a reorganization of cells and tissue takes place as the surrounding cells attempt to limit the injury, repair the damage, and restore normal architecture of the brain. This tissue remodeling requires de novo synthesis of genes and proteins which enables cells to actively change their relationship with the existing extracellular matrix and with other cells to reorganize the damaged tissue. We have identified two key molecular components… CONTINUE READING
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