• DOI:10.1146/ANNUREV.BIOCHEM.67.1.609
Corpus ID: 14638091

Matrix proteoglycans: from molecular design to cellular function.

@article{Iozzo1998MatrixPF,
  title={Matrix proteoglycans: from molecular design to cellular function.},
  author={R. Iozzo},
  journal={Annual review of biochemistry},
  year={1998},
  volume={67},
  pages={
          609-52
        }
}

• R. Iozzo
• Published 1998
• Biology, Medicine
• Annual review of biochemistry

The proteoglycan superfamily now contains more than 30 full-time molecules that fulfill a variety of biological functions. Proteoglycans act as tissue organizers, influence cell growth and the maturation of specialized tissues, play a role as biological filters and modulate growth-factor activities, regulate collagen fibrillogenesis and skin tensile strength, affect tumor cell growth and invasion, and influence corneal transparency and neurite outgrowth. Additional roles, derived from studies… Expand

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