Matrix metalloproteinases and tissue inhibitors of metalloproteinases in gingival crevicular fluid during orthodontic tooth movement.

@article{Bildt2009MatrixMA,
  title={Matrix metalloproteinases and tissue inhibitors of metalloproteinases in gingival crevicular fluid during orthodontic tooth movement.},
  author={Miriam M Bildt and Marjon Bloemen and A M Kuijpers-Jagtman and Johannes W. Von den Hoff},
  journal={European journal of orthodontics},
  year={2009},
  volume={31 5},
  pages={
          529-35
        }
}
Orthodontic tooth movement requires extensive re-modelling of the periodontium. Matrix metalloproteinases (MMPs) degrade the extracellular matrix during re-modelling, while their activity is regulated by the tissue inhibitors of metalloproteinases (TIMPs). The aim of this study was to investigate differences in MMP and TIMP levels in the gingival crevicular fluid (GCF) at the resorption and apposition sides of orthodontically moved teeth, and to compare these with control teeth. GCF samples… CONTINUE READING
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