Matrix metalloproteinases and their inhibitors in the chamber angle of normal eyes and patients with primary open-angle glaucoma and exfoliation glaucoma

@article{Rnkk2006MatrixMA,
  title={Matrix metalloproteinases and their inhibitors in the chamber angle of normal eyes and patients with primary open-angle glaucoma and exfoliation glaucoma},
  author={Seppo R{\"o}nkk{\"o} and Petri K Rekonen and Kai Kaarniranta and Tuomo J Puustj{\"a}rvi and Markku E. Ter{\"a}svirta and Hannu Uusitalo},
  journal={Graefe's Archive for Clinical and Experimental Ophthalmology},
  year={2006},
  volume={245},
  pages={697-704}
}
In glaucoma, extensive pathological changes occur in the trabecular meshwork (TM) and juxtacanalicular tissue of the chamber angle. Aqueous humor drainage is disturbed due to the accumulation of extracellular matrix (ECM) material in the outflow system. Matrix metalloproteinases (MMPs) remodel ECM material and, thus, they may have a role in regulating outflow facility and intraocular pressure (IOP). This study examined the expression of MMPs and tissue inhibitors of MMPs (TIMPs) in the chamber… CONTINUE READING

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Matrix metalloproteinases and their inhibitors in aqueous humor of patients with pseudoexfoliation syndrome / glaucoma and primary open - angle glaucoma

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