Matrix metalloproteinases and myocardial infarction.

  title={Matrix metalloproteinases and myocardial infarction.},
  author={Wannakorn Phatharajaree and Arintaya Phrommintikul and Nipon Chattipakorn},
  journal={The Canadian journal of cardiology},
  volume={23 9},
Acute myocardial infarction (AMI) is currently one of the most important health problems in many countries around the world. Following AMI, many cytokines and proteolytic enzymes are released. Among these, matrix metalloproteinases (MMPs) are important proteolytic enzymes that lead to degradation of the extracellular matrix and to changes in cardiomyocytes in both infarcted and noninfarcted myocardium. This process is known as cardiac remodelling. It has been demonstrated that more than one… CONTINUE READING


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