Matrix metalloproteinases 2 and 9 and their tissue inhibitors in low malignant potential ovarian tumors.

@article{Mtt2004MatrixM2,
  title={Matrix metalloproteinases 2 and 9 and their tissue inhibitors in low malignant potential ovarian tumors.},
  author={Milla M{\"a}{\"a}tt{\"a} and Markku J Santala and Ylermi M Soini and Anne Talvensaari-Mattila and Taina Turpeenniemi-Hujanen},
  journal={Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine},
  year={2004},
  volume={25 4},
  pages={188-92}
}
OBJECTIVES This study aimed to analyze the expression of matrix metalloproteinases 2 (MMP-2) and 9 (MMP-9) and their tissue inhibitors TIMP-1 and TIMP-2 in low malignant potential (LMP) ovarian tumors and to compare these values with those recorded for benign and malignant ovarian neoplasms. METHODS A total of 53 ovarian tumors (16 benign, 15 LMP and 22 malignant) were evaluated by immunohistochemistry for the expression of MMP-2, MMP-9, TIMP-1 and TIMP-2. RESULTS MMP-2 expression was found… CONTINUE READING