Matrix metalloproteinases (MMPs) are required for re-epithelialization of cutaneous wounds

@article{gren1999MatrixM,
  title={Matrix metalloproteinases (MMPs) are required for re-epithelialization of cutaneous wounds},
  author={Magnus S {\AA}gren},
  journal={Archives of Dermatological Research},
  year={1999},
  volume={291},
  pages={583-590}
}
Abstract Matrix metalloproteinases (MMPs) are neutral zinc-dependent endopeptidases with substrate specificity for most extracellular matrix molecules. MMPs participate in physiological and pathological biological processes. In wound repair, several MMPs are upregulated in migrating epithelium although the biological significance of their presence is unknown. To elucidate the role of MMPs in epithelial migration of cutaneous wounds, a broad-spectrum synthetic MMP inhibitor (GM 6001, 10 mg/ml… CONTINUE READING

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