Matrix metalloproteinase polymorphisms and bladder cancer risk.

  title={Matrix metalloproteinase polymorphisms and bladder cancer risk.},
  author={Andrew Karim Kader and Lina Shao and Colin P. N. Dinney and Matthew B. Schabath and Yunfei Wang and Jun Liu and Jian Gu and Herbert Barton Grossman and Xifeng Wu},
  journal={Cancer research},
  volume={66 24},
Matrix metalloproteinases (MMP) contribute to tumor microenvironment and are associated with bladder cancer. A study examining the association between MMP polymorphisms and bladder cancer risk has never been published. We analyzed the association of 11 single nucleotide polymorphisms (SNPs) and one microsatellite polymorphism in MMP genes MMP-1, MMP-2, MMP-3, MMP-8, MMP-9, and MMP-12 with bladder cancer risk in 560 Caucasian patients and 560 controls matched on age, gender, and ethnicity… CONTINUE READING
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