Matrix metalloproteinase inhibitors as therapy for inflammatory and vascular diseases

Abstract

Matrix metalloproteinases (MMPs) have outgrown the field of extracellular-matrix biology and have progressed towards being important regulatory molecules in cancer and inflammation. This rise in status was accompanied by the development of various classes of inhibitors. Although clinical trials with synthetic inhibitors for the treatment of cancer were… (More)
DOI: 10.1038/nrd2308

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