Matrix metalloproteinase inhibitor modulates esterase-catalyzed degradation of resin-dentin interfaces.

@article{Serkies2016MatrixMI,
  title={Matrix metalloproteinase inhibitor modulates esterase-catalyzed degradation of resin-dentin interfaces.},
  author={Kyle Brandon Serkies and Reena Garcha and Laura E Tam and Grace Mendonça Dias de Souza and Y Finer},
  journal={Dental materials : official publication of the Academy of Dental Materials},
  year={2016},
  volume={32 12},
  pages={
          1513-1523
        }
}
OBJECTIVE Assess the modulating effect of matrix metalloproteinase (MMP) inhibition on simulated human salivary enzyme (SHSE)-catalyzed degradation of interfacial fracture-toughness (FT) of self-etched and total-etched resin-dentin interfaces. METHODS Miniature short-rod FT specimens (N=10/group) containing a resin composite bonded to human dentin, using a self-etch (Easy Bond, EB) or a total-etch (Scotchbond, SB) adhesives, were prepared with and without application of an MMP inhibitor… CONTINUE READING
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