Matrix metalloproteinase gene polymorphisms in patients with rheumatoid arthritis

@article{Scherer2009MatrixMG,
  title={Matrix metalloproteinase gene polymorphisms in patients with rheumatoid arthritis},
  author={Sabrina Scherer and Thais Barboza de Souza and Juliana de Paoli and Claiton Viegas Brenol and Ricardo Machado Xavier and Jo{\~a}o Carlos Tavares Brenol and Jos{\'e} Artur Bogo Chies and Daniel Simon},
  journal={Rheumatology International},
  year={2009},
  volume={30},
  pages={369-373}
}
Several genetic factors seem to be involved in the pathogenesis of rheumatoid arthritis (RA). The aim of this study was to analyze whether functional polymorphisms in the promoter region of the MMP-1, -3 and -9 genes were associated with RA. The study population comprises 110 RA patients and 100 healthy controls. The –1607 1G/2G MMP-1, –1171 5A/6A MMP-3, and –1562 C/T MMP-9 polymorphisms were analyzed. The frequency of the 5A allele of MMP-3 gene was significantly higher in the controls when… CONTINUE READING

Tables and Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 11 CITATIONS

Association of tumor necrosis factor–α (G-308A) genetic variant with matrix metalloproteinase–9 activity and joint destruction in early rheumatoid arthritis

Sonja Stojanovic, Bojana Stamenkovic, +4 authors Dusica Pavlovic
  • Clinical Rheumatology
  • 2017
VIEW 1 EXCERPT
CITES RESULTS

Matrix metalloproteinase gene polymorphisms and susceptibility to systemic sclerosis.

  • Genetics and molecular research : GMR
  • 2016
VIEW 2 EXCERPTS
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 24 REFERENCES

Allele-specific MMP-3 transcription under in vivo conditions.

  • Biochemical and biophysical research communications
  • 2006
VIEW 1 EXCERPT