Matrix metalloproteinase 9 modulates collagen matrices and wound repair.

@article{LeBert2015MatrixM9,
  title={Matrix metalloproteinase 9 modulates collagen matrices and wound repair.},
  author={Danny LeBert and Jayne M Squirrell and Julie Rindy and Elizabeth Broadbridge and Yuming Lui and Anna Zakrzewska and Kevin W. Eliceiri and Annemarie H. Meijer and Anna Huttenlocher},
  journal={Development},
  year={2015},
  volume={142 12},
  pages={2136-46}
}
Acute and chronic injuries are characterized by leukocyte infiltration into tissues. Although matrix metalloproteinase 9 (Mmp9) has been implicated in both conditions, its role in wound repair remains unclear. We previously reported a zebrafish chronic inflammation mutant caused by an insertion in the hepatocyte growth factor activator inhibitor gene 1 (hai1; also known as spint1) that is characterized by epithelial extrusions and neutrophil infiltration into the fin. Here, we performed a… CONTINUE READING
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