Matrix metalloproteinase-9 expression in renal biopsies of patients with HIV-associated nephropathy.

@article{Ahuja2003MatrixME,
  title={Matrix metalloproteinase-9 expression in renal biopsies of patients with HIV-associated nephropathy.},
  author={Tejinder S. Ahuja and Anisa Gopalani and Peter Sw Davies and Harleen Ahuja},
  journal={Nephron. Clinical practice},
  year={2003},
  volume={95 3},
  pages={c100-4}
}
BACKGROUND/AIMS The normal architecture and function of the kidney are maintained by a critical turnover of the extracellular matrix (ECM). Although increased synthesis of ECM leads to progression of renal failure, the role of degradation of ECM by metalloproteinases in progressive nephropathies is unclear. Recently, in an animal model of membranous glomerulonephritis (Heymann nephritis), visceral epithelial cell (VEC) injury has been found to rapidly increase matrix metalloproteinase-9 (MMP-9… CONTINUE READING
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