Matrix metalloproteinase-9/gelatinase B is required for process outgrowth by oligodendrocytes.

Abstract

Oligodendrocytes (OLs) extend processes to contact axons as a prerequisite step in myelin formation. As the OL processes migrate toward their axonal targets, they modify adhesion to their substrate, an event that may be regulated by matrix metalloproteinases (MMPs). In the mouse optic nerve, MMP-9/gelatinase B increases during myelin formation. Although… (More)

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Cite this paper

@article{Oh1999MatrixMB, title={Matrix metalloproteinase-9/gelatinase B is required for process outgrowth by oligodendrocytes.}, author={Laura Oh and Peter Hj\orringaard Larsen and Craig A. Krekoski and D. R. Edwards and F Daniel Donovan and Zena Werb and V. Wee Yong}, journal={The Journal of neuroscience : the official journal of the Society for Neuroscience}, year={1999}, volume={19 19}, pages={8464-75} }