Matrix metalloproteinase-2, -9, and -12 gene polymorphisms in generalized aggressive periodontitis.

@article{Grkan2007MatrixM,
  title={Matrix metalloproteinase-2, -9, and -12 gene polymorphisms in generalized aggressive periodontitis.},
  author={A. G{\"u}rkan and G. Emingil and B. Saygan and G. Atilla and S. Çinarcik and T. K{\"o}se and A. Berdeli},
  journal={Journal of periodontology},
  year={2007},
  volume={78 12},
  pages={
          2338-47
        }
}
BACKGROUND Matrix metalloproteinases (MMPs) are involved in periodontal tissue remodeling and degradation. Polymorphisms in the promoter region of the MMP-2 and -9 genes and in the coding region of the MMP-12 gene could affect transcription and the function of these enzymes. The aim of the present study was to determine the association between the aforementioned MMP polymorphisms and generalized aggressive periodontitis (GAgP). METHODS Genomic DNA was obtained from the peripheral blood of 92… Expand
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Matrix metalloproteinase-2, -9, and tissue inhibitor of MMP-2 gene polymorphisms in Taiwanese periodontitis patients
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Alliance of matrix metalloproteinase-9 (MMP-9) promoter gene polymorphism with chronic and aggressive periodontitis in Indian population
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Matrix metalloproteinase (MMP)-8 and tissue inhibitor of MMP-1 (TIMP-1) gene polymorphisms in generalized aggressive periodontitis: gingival crevicular fluid MMP-8 and TIMP-1 levels and outcome of periodontal therapy.
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Association of matrix metalloproteinase (MMP)-1, 3, 9, interleukin (IL)-2, 8 and cyclooxygenase (COX)-2 gene polymorphisms with chronic periodontitis in a Chinese population.
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Association of Common Variants in MMPs with Periodontitis Risk
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Matrix metalloproteinase gene polymorphisms and periodontitis susceptibility: a meta-analysis involving 6,162 individuals
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Association of MMP-2-753C>T and MMP-9-1562C>T Polymorphisms with Chronic/Aggressive Periodontitis Risk: A Systematic Review and Meta-Analysis
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The association of MMP-9 and IL-18 gene promoter polymorphisms with gingivitis in adolescents.
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The Association of Matrix Metalloproteinase Gene Polymorphisms and Periodontitis: An Overview
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