Matrix metalloproteinase-19 inhibits growth of endothelial cells by generating angiostatin-like fragments from plasminogen

@inproceedings{Brauer2011MatrixMI,
  title={Matrix metalloproteinase-19 inhibits growth of endothelial cells by generating angiostatin-like fragments from plasminogen},
  author={Rena Brauer and Inken Maria Beck and Martin Roderfeld and Elke Roeb and Radislav Sedlacek},
  booktitle={BMC Biochemistry},
  year={2011}
}
BackgroundAngiogenesis is the process of forming new blood vessels from existing ones and requires degradation of the vascular basement membrane and remodeling of extracellular matrix (ECM) in order to allow endothelial cells to migrate and invade into the surrounding tissue. Matrix metalloproteinases (MMPs) are considered to play a central role in the remodeling of basement membranes and ECM. However, MMPs contribute to vascular remodeling not only by degrading ECM components. Specific MMPs… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-9 OF 9 CITATIONS

Angiogenic potential of extracellular matrix of human amniotic membrane

  • Tissue Engineering and Regenerative Medicine
  • 2016
VIEW 2 EXCERPTS
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 43 REFERENCES

Similar Papers

Loading similar papers…