Matrix metalloproteinase 12 promotes tumor propagation in the lung.

@article{Ella2018MatrixM1,
  title={Matrix metalloproteinase 12 promotes tumor propagation in the lung.},
  author={Ezra Ella and Yaniv Harel and Michal Abraham and H. Wald and Ofra Benny and Adi Karsch-Bluman and Dive Vincent and Devel Laurent and Gharachorlou Amir and Uzi Izhar and Oz M. Shapira and D. Yoon and Hyun-Sung Lee and David J. Sugarbaker and Bryan M. Burt and Amnon Peled and Ori Wald},
  journal={The Journal of thoracic and cardiovascular surgery},
  year={2018},
  volume={155 5},
  pages={
          2164-2175.e1
        }
}
OBJECTIVE Past studies are inconsistent with regard to the role of matrix metalloproteinase 12 in lung tumorigenesis. This is due, in part, to differential tumorigenesis based on tumor-derived versus immune-derived matrix metalloproteinase 12 expression. Our study aims to thoroughly dissect the role of matrix metalloproteinase 12 in lung tumorigenesis. METHODS We tested matrix metalloproteinase 12 expression and the association with prognosis using a tissue array and a published non-small… CONTINUE READING
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