Matrix metalloproteinase-10 expression is induced during hepatic injury and plays a fundamental role in liver tissue repair.

@article{GarcaIrigoyen2014MatrixME,
  title={Matrix metalloproteinase-10 expression is induced during hepatic injury and plays a fundamental role in liver tissue repair.},
  author={Oihane Garc{\'i}a-Irigoyen and Simone Carotti and Mar{\'i}a Ujue Latasa and Iker Uriarte and Maite G. Fern{\'a}ndez-Barrena and Maria Laura B. de Elizalde and Raquel Urtasun and Umberto Vespasiani-Gentilucci and Sergio Morini and Jes{\'u}s Mar{\'i}a Banales and William C. Parks and Jos{\'e} A. Rodr{\'i}guez and Josune Orbe and Jes{\'u}s Prieto and Jos{\'e} Antonio Matos P{\'a}ramo and Carmen Berasain and Mat{\'i}as A. Avila},
  journal={Liver international : official journal of the International Association for the Study of the Liver},
  year={2014},
  volume={34 7},
  pages={e257-70}
}
BACKGROUND & AIMS Upon tissue injury, the liver mounts a potent reparative and regenerative response. A role for proteases, including serine and matrix metalloproteinases (MMPs), in this process is increasingly recognized. We have evaluated the expression and function of MMP10 (stromelysin-2) in liver wound healing and regeneration. METHODS The hepatic expression of MMP10 was examined in two murine models: liver regeneration after two-thirds partial hepatectomy (PH) and bile duct ligation… CONTINUE READING

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