Matrix metalloproteases: underutilized targets for drug delivery.

@article{Vartak2007MatrixMU,
  title={Matrix metalloproteases: underutilized targets for drug delivery.},
  author={Deepali G. Vartak and Richard A. Gemeinhart},
  journal={Journal of drug targeting},
  year={2007},
  volume={15 1},
  pages={
          1-20
        }
}
Pathophysiological molecules in the extracellular environment offer excellent targets that can be exploited for designing drug targeting systems. Matrix metalloproteases (MMPs) are a family of extracellular proteolytic enzymes that are characterized by their overexpression or overactivity in several pathologies. Over the last two decades, the MMP literature reveals heightened interest in the research involving MMP biology, pathology and targeting. This review describes various strategies that… CONTINUE READING

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