Matrix degradation inhibitory effect of Schisandra fructus on human articular cartilage and chondrocytes.

@article{Choi2006MatrixDI,
  title={Matrix degradation inhibitory effect of Schisandra fructus on human articular cartilage and chondrocytes.},
  author={Soo Im Choi and So Ra Park and Tae Ryeon Heo},
  journal={Journal of ethnopharmacology},
  year={2006},
  volume={106 2},
  pages={279-84}
}
The purpose of this study is to assess the protective effects exerted by Schisandra fructus (SF) on hyaluronidase (HAase) and the recombinant human interleukin-1beta (IL-1beta) induced matrix degradation in human articular cartilage and chondrocytes. The effect of SF on the matrix gene expression of immortalized chondrocyte cell line C-28/I2 treated with HAase was investigated using a reverse transcription polymerase chain reaction (RT-PCR). In addition, the effects of SFEA on HAase and IL… CONTINUE READING