Matrix-comparative genomic hybridization from multicenter formalin-fixed paraffin-embedded colorectal cancer tissue blocks

@inproceedings{Fensterer2006MatrixcomparativeGH,
  title={Matrix-comparative genomic hybridization from multicenter formalin-fixed paraffin-embedded colorectal cancer tissue blocks},
  author={Heiko Fensterer and Bernhard Radlwimmer and Joern Straeter and Malte Buchholz and Daniela E. Aust and Catherine Juli{\'e} and François Radvanyi and Bernard M Nordlinger and Claudio Belluco and Eric Van Cutsem and C. H. K{\"o}hne and Hans A. Kestler and Carsten Schwaenen and Michelle Nessling and Manfred Paul Lutz and Peter Lichter and Thomas Matthias Gress},
  booktitle={BMC Cancer},
  year={2006}
}
The identification of genomic signatures of colorectal cancer for risk stratification requires the study of large series of cancer patients with an extensive clinical follow-up. Multicentric clinical studies represent an ideal source of well documented archived material for this type of analyses. To verify if this material is technically suitable to perform matrix-CGH, we performed a pilot study using macrodissected 29 formalin-fixed, paraffin-embedded tissue samples collected within the… CONTINUE READING

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