Matrix attachment regions as targets for retroviral integration

Abstract

The randomness of retroviral integration has been debated for many years. Recent evidence indicates that integration site selection is not random, and that it is influenced by both viral and cellular factors. To study the role of DNA structure in site selection, retroviral integration near matrix attachment regions (MARs) was analyzed for three different… (More)
DOI: 10.1186/1743-422X-2-68

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