Matrix-assisted laser desorption ionization mass spectrometry for the analysis of monosulfated oligosaccharides.

@article{Dai1997MatrixassistedLD,
  title={Matrix-assisted laser desorption ionization mass spectrometry for the analysis of monosulfated oligosaccharides.},
  author={Yongsheng Dai and Randy M. Whittal and Craig A Bridges and Yukihiro Isogai and Ole Hindsgaul and Lin Li},
  journal={Carbohydrate research},
  year={1997},
  volume={304 1},
  pages={1-9}
}
Sulfated oligosaccharides are an important class of compounds in the field of glycobiology. Mass spectrometric analysis of these molecules is challenging due to their readiness to dissociate in sample preparation and their tendency to fragment during ionization. Moreover, their presence in small quantity in biological systems poses additional problems. We report the development of a mass spectrometric method based on matrix-assisted laser desorption ionization (MALDI) in a time-lag focusing… CONTINUE READING