Matrix Metalloproteinase Chronic Matrix Metalloproteinase Inhibition Retards Age-Associated Arterial Proinflammation and Increase in Blood Pressure

@inproceedings{Wang2012MatrixMC,
  title={Matrix Metalloproteinase Chronic Matrix Metalloproteinase Inhibition Retards Age-Associated Arterial Proinflammation and Increase in Blood Pressure},
  author={Mingyi Wang and Jing Zhang and Richard S. Telljohann and Liqun Jiang and James Wu and Robert E. Monticone and Kapil Kapoor and Mark I. Talan and Edward G. Lakatta},
  year={2012}
}
Age-associated arterial remodeling involves arterial wall collagen deposition and elastin fragmentation, as well as an increase in arterial pressure. This arterial remodeling is linked to proinflammatory signaling, including transforming growth factor1, monocyte chemoattractant protein 1, and proendothelin 1, activated by extracellular matrix… CONTINUE READING