Matrix Gla protein is associated with coronary artery calcification as assessed by electron-beam computed tomography.

@article{Jono2004MatrixGP,
  title={Matrix Gla protein is associated with coronary artery calcification as assessed by electron-beam computed tomography.},
  author={Shuichi Jono and Yuji Ikari and Cees Vermeer and Paul Dissel and Kotaro Hasegawa and Atsushi Shioi and Hiromichi Taniwaki and Akane Kizu and Yoshiki Nishizawa and Shigeru Saito},
  journal={Thrombosis and haemostasis},
  year={2004},
  volume={91 4},
  pages={
          790-4
        }
}
Matrix Gla protein (MGP) is an extracellular matrix protein with wide tissue distribution. It has been demonstrated that the expression of MGP is detected not only in the normal blood vessels but also calcified atherosclerotic plaques, and that MGP deficient mice develop extensive arterial calcification. MGP is thought to be a regulator of vascular calcification. A recent clinical study demonstrates the association between polymorphisms of the MGP gene and increased risk of myocardial… CONTINUE READING

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