Matrix Assisted Ionization in Vacuum, a Sensitive and Widely Applicable Ionization Method for Mass Spectrometry

@article{Trimpin2013MatrixAI,
  title={Matrix Assisted Ionization in Vacuum, a Sensitive and Widely Applicable Ionization Method for Mass Spectrometry},
  author={Sarah Trimpin and Ellen D. Inutan},
  journal={Journal of The American Society for Mass Spectrometry},
  year={2013},
  volume={24},
  pages={722-732}
}
  • S. Trimpin, E. D. Inutan
  • Published 2013
  • Chemistry, Medicine
  • Journal of The American Society for Mass Spectrometry
AbstractAn astonishingly simple new method to produce gas-phase ions of small molecules as well as proteins from the solid state under cold vacuum conditions is described. This matrix assisted ionization vacuum (MAIV) mass spectrometry (MS) method produces multiply charged ions similar to those that typify electrospray ionization (ESI) and uses sample preparation methods that are nearly identical to matrix-assisted laser desorption/ionization (MALDI). Unlike these established methods, MAIV does… Expand
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