Matrilysin (MMP-7) as a significant determinant of malignant potential of early invasive colorectal carcinomas

  title={Matrilysin (MMP-7) as a significant determinant of malignant potential of early invasive colorectal carcinomas},
  author={Tadahiko Masaki and Hiroyoshi Matsuoka and Masanori Sugiyama and Nobutsugu Abe and Akiteru Goto and Akiko Sakamoto and Yutaka Atomi},
  journal={British Journal of Cancer},
  pages={1317 - 1321}
Matrix metalloproteinases play a crucial role in tumour invasion and mestasis. Matrilysin (MMP-7) has been shown to correlate with nodal or distant metastasis in colorectal carcinomas; however, its implication in early invasive colorectal carcinomas has not been determined. This study was undertaken to clarify the association of matrilysin expression with clinicopathologic parameters in early invasive colorectal carcinomas. 38 early invasive colorectal carcinomas treated by local excision or… CONTINUE READING

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