Mathematical treatment of isotopologue and isotopomer speciation and fractionation in biochemical kinetics

  title={Mathematical treatment of isotopologue and isotopomer speciation and fractionation in biochemical kinetics},
  author={Federico Maggi and William J. Riley},
  journal={Geochimica et Cosmochimica Acta},
  • F. Maggi, W. Riley
  • Published 1 November 2009
  • Biology
  • Geochimica et Cosmochimica Acta
Nonlinear dynamic model describing the fractionation of stable nitrogen isotopes in denitrification process with nitrous oxide formation
Soil thawing in permafrost zones can lead to the formation of readily digestible organic matter. This intensifies nitrate denitrification processes, leading to the formation of nitrous oxide, which
On the mechanisms of sulfur isotope fractionation during microbial sulfate reduction
Underlying all applications of sulfur isotope analyses is our understanding of isotope systematics. This dissertation tests some fundamental assumptions and assertions, drawn from equilibrium theory
The Thermodynamic Links between Substrate, Enzyme, and Microbial Dynamics in Michaelis–Menten–Monod Kinetics
It is shown that cells have optimal growth when the catabolic (differential) free energy of activation decreases the cell free energy harvest required to duplicate their internal structures as long as electrons for anabolism are available.
Stable Isotope Fractionations in Biogeochemical Reactive Transport
Author(s): Druhan, Jennifer Lea | Advisor(s): DePaolo, Donald J | Abstract: Characterizing the reactivity and fate of solutes in groundwater presents a formidable challenge in that these environments
The effect of temperature on the rate, affinity, and 15N fractionation of NO3− during biological denitrification in soils
Nine independent experiments of NO3− denitrification were analysed using the Arrhenius law and the Eyring’s transition-state theory to highlight how temperature affects reaction rate constants,
The effect of (15)N to (14)N ratio on nitrification, denitrification and dissimilatory nitrate reduction.
  • F. Tang, F. Maggi
  • Environmental Science
    Rapid communications in mass spectrometry : RCM
  • 2012
The results enable the assumption of constant reaction parameters to be rejected, and the implications of δ-dependent (variable) reaction parameters extend beyond the study-case analysed here to all instances in which high and variable isotopic enrichments occur.


Quantification of sequential chlorinated ethene degradation by use of a reactive transport model incorporating isotope fractionation.
The developed multistep isotope fractionation reactive transport model (IF-RTM) adequately simulated reductive dechlorination of tetrachloroethene (PCE) to ethene in a microcosm experiment and can be incorporated in 3D solute transport models to enable quantification of sequential CAH degradation in the field by CSIA.
Experimental determination of nitrogen kinetic isotope fractionation: Some principles; illustration for the denitrification and nitrification processes
SummaryA few principles relative to the presentation and use of nitrogen stable isotopic data are briefly reviewed. Some classical relationships between the isotope composition of a substrate
Impact of bioavailability restrictions on microbially induced stable isotope fractionation. 1. Theoretical calculation.
The microbial degradation of organic substrates often exhibits a fractionation of stable isotopes which leads to an enrichment of the heavier isotope in the remaining substrate, and changes in observed isotope fractionation might occur while contaminant concentration decreases along a flow path.
Fractionation of N2O isotopomers during production by denitrifiers
A new concept linking observable stable isotope fractionation to transformation pathways of organic pollutants.
The evaluation scheme presented bridges a gap between basic and environmental (bio)chemistry and provides insight into factors that control the magnitude of bulk isotope fractionation factors.
Transient competitive complexation in biological kinetic isotope fractionation explains non-steady isotopic effects: Theory and application to denitrification in soils
Transient competitive complexation in biological kinetic isotope fractionation explains non-steady isotopic e-ects in soils and theory and application to denitrification in soils is explained.
Evidence of Substantial Carbon Isotope Fractionation among Substrate, Inorganic Carbon, and Biomass during Aerobic Mineralization of 1,2-Dichloroethane byXanthobacter autotrophicus
Carbon isotope fractionation during aerobic mineralization of 1,2-dichloroethane by Xanthobacter autotrophicusGJ10 leads to 1, 2-DCA, inorganic carbon, and biomass with characteristic carbon isotope compositions, which may be used to trace the process in contaminated environments.
Stable isotope discrimination during soil denitrification: Production and consumption of nitrous oxide
Measuring the stable isotope composition of nitrous oxide (N2O) evolved from soil could improve our understanding of the relative contributions of the main microbial processes (nitrification and