Mathematical simplification of a PET blood flow model.

  title={Mathematical simplification of a PET blood flow model.},
  author={R F Muzic and A. Dennis Nelson and Floro Miraldi},
  journal={IEEE transactions on medical imaging},
  volume={9 2},
The positron emission tomography (PET) H(2)(15)O bolus injection model for cerebral blood flow (CBF) requires calculation of a certain double integral that, when calculated, provides the pixel values of a reconstructed image (PET number) in terms of the tissue flow, the arterial input function, a decay constant for (15)O, the partition coefficient and a camera calibration constant that relates the flow-dependent integrated tissue activity to the measured PET number (cts/pixel). The tissue… CONTINUE READING