Mathematical modelling of non-stationary fluctuation analysis for studying channel properties of synaptic AMPA receptors.

@article{Benke2001MathematicalMO,
  title={Mathematical modelling of non-stationary fluctuation analysis for studying channel properties of synaptic AMPA receptors.},
  author={Tim Benke and Andreas L{\"u}thi and Mary J. Palmer and Martin Wikstr{\"o}m and William Way Anderson and John T.R Isaac and Graham L Collingridge},
  journal={The Journal of physiology},
  year={2001},
  volume={537 Pt 2},
  pages={407-20}
}
1. The molecular properties of synaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptors are an important factor determining excitatory synaptic transmission in the brain. Changes in the number (N) or single-channel conductance (gamma) of functional AMPA receptors may underlie synaptic plasticity, such as long-term potentiation (LTP) and long-term depression (LTD). These parameters have been estimated using non-stationary fluctuation analysis (NSFA). 2. The validity of NSFA… CONTINUE READING
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