Mathematical modelling and evaluation of performance of cuboid packed-bed devices for chromatographic separations.

@article{Ghosh2017MathematicalMA,
  title={Mathematical modelling and evaluation of performance of cuboid packed-bed devices for chromatographic separations.},
  author={Raja Ghosh and Guoqiang Chen},
  journal={Journal of chromatography. A},
  year={2017},
  volume={1515},
  pages={
          138-145
        }
}
In a recent paper, box-shaped or cuboid packed bed devices have been proposed as alternative to columns for chromatographic separations. We first propose a mathematical model for residence time distribution in such devices. Based on it, we examine factors likely to affect separation performance, and verify the predictions of our mathematical model by conducting tracer experiments. We then compare the performance of two commercial columns with their respective equivalent cuboid packed-bed… CONTINUE READING

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