Mathematical model of the metabolism of 123I-16-iodo-9-hexadecenoic acid in an isolated rat heart. Validation by comparison with experimental measurements

@article{Dubois1986MathematicalMO,
  title={Mathematical model of the metabolism of 123I-16-iodo-9-hexadecenoic acid in an isolated rat heart. Validation by comparison with experimental measurements},
  author={Francis Dubois and J. C. Depresseux and Laurence Bontemps and Luc Demaison and Christiane K{\'e}riel and J C Mathieu and Claude Pernin and Dani{\`e}le Marti-Batlle and Michel Vidal and Pierre Cuchet and Michel Comet},
  journal={European Journal of Nuclear Medicine},
  year={1986},
  volume={11},
  pages={453-458}
}
The aim of the present study was to demonstrate that it is possible to estimate the intracellular metabolism of a fatty acid labelled with iodine using external radioactivity measurements. 123I-16-iodo-9-hexadecenoic acid (IHA) was injected close to the coronary arteries of isolated rat hearts perfused according to the Langendorff technique. The time course… CONTINUE READING