Mathematical model for the androgenic regulation of the prostate in intact and castrated adult male rats.

@article{Potter2006MathematicalMF,
  title={Mathematical model for the androgenic regulation of the prostate in intact and castrated adult male rats.},
  author={Laura K. Potter and Michael Gary Zager and H. Arnold Barton},
  journal={American journal of physiology. Endocrinology and metabolism},
  year={2006},
  volume={291 5},
  pages={
          E952-64
        }
}
The testicular-hypothalamic-pituitary axis regulates male reproductive system functions. Understanding these regulatory mechanisms is important for assessing the reproductive effects of environmental and pharmaceutical androgenic and antiandrogenic compounds. A mathematical model for the dynamics of androgenic synthesis, transport, metabolism, and regulation of the adult rodent ventral prostate was developed on the basis of a model by Barton and Anderson (1997). The model describes the systemic… CONTINUE READING

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