Mathematical and pharmacokinetic modelling of epidermal and dermal transport processes.

@article{Anissimov2013MathematicalAP,
  title={Mathematical and pharmacokinetic modelling of epidermal and dermal transport processes.},
  author={Yuri G. Anissimov and Owen G. Jepps and Yuri Dancik and Michael S. Roberts},
  journal={Advanced drug delivery reviews},
  year={2013},
  volume={65 2},
  pages={
          169-90
        }
}
Topical delivery to the various regions of the skin and underlying tissues, transdermal drug delivery and dermal exposure to environmental chemicals are important areas of research. Mathematical models of epidermal and dermal transport, involving penetration of a solute through various layers of the skin, metabolism in the skin and its subsequent distribution and clearance into systemic circulation from underlying tissues, play an essential role in this research area and are reviewed in this… CONTINUE READING
Highly Cited
This paper has 87 citations. REVIEW CITATIONS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 31 extracted citations

Transdermal Drug Delivery and Percutaneous Absorption : Mathematical Modeling Perspectives

Filippo de Montea, Giuseppe Pontrellib, Sid M. Beckerc
2015
View 7 Excerpts
Method Support
Highly Influenced

88 Citations

01020'14'16'18
Citations per Year
Semantic Scholar estimates that this publication has 88 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
Showing 1-10 of 152 references

Mathematical models in percutaneous absorption

M. S. Roberts, Y. G. Anissimov
in: R.L. Bronaugh, H.I. Maibach (Eds.), Percutaneous Absorption Drugs — Cosmetics, Mechanisms, Methodology, Marcel Dekker, New York • 2005
View 13 Excerpts
Highly Influenced

Partitioning

K. Kretsos, M. A. Miller, G. Zamora-Estrada, G. B. Kasting
diffusivity and clearance of skin permeants in mammalian dermis, Int. J. Pharm. 346 • 2008
View 7 Excerpts
Highly Influenced

A geometrical model of dermal capillary clearance.

Mathematical biosciences • 2007
View 5 Excerpts
Highly Influenced