Mathematical Modeling of the Influence of RKIP on the ERK Signaling Pathway


This paper investigates the influence of the Raf Kinase Inhibitor Protein (RKIP) on the Extracellular signal Regulated Kinase (ERK) signaling pathway through mathematical modeling and simulation. Using nonlinear ordinary differential equations to represent biochemical reactions in the pathway, we suggest a technique for parameter estimation, utilizing time… (More)
DOI: 10.1007/3-540-36481-1_11


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