Maternally transmitted histocompatibility antigen of mice: a hydrophobic peptide of a mitochondrially encoded protein.

@article{Loveland1990MaternallyTH,
  title={Maternally transmitted histocompatibility antigen of mice: a hydrophobic peptide of a mitochondrially encoded protein.},
  author={B E Loveland and Chen Ran Wang and Hiromichi Yonekawa and Evan Hermel and Kirsten Fischer Lindahl},
  journal={Cell},
  year={1990},
  volume={60 6},
  pages={971-80}
}
MTF, a murine minor histocompatibility antigen, is maternally inherited and thought to be encoded by a mitochondrial gene. We sequenced the entire mitochondrial genomes from three strains that differ in MTF Mtf beta, Mtf gamma, and Mtf delta) and compared the sequences with the known, Mtf alpha, mitochondrial DNA sequence. We found only one site where all four genomes differed, affecting amino acid residue 6 of ND1, a subunit of NADH dehydrogenase. Incubation of non-Mtf alpha target cells with… CONTINUE READING
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