Maternal stress retards fetal development in mice with transcriptome-wide impact on gene expression profiles of the limb.

@article{Choe2011MaternalSR,
  title={Maternal stress retards fetal development in mice with transcriptome-wide impact on gene expression profiles of the limb.},
  author={Han Kyoung Choe and Gi Hoon Son and Sooyoung Chung and Myungjin Kim and Woong Sun and Hyun Kim and Dongho Geum and Kyungjin Kim},
  journal={Stress},
  year={2011},
  volume={14 2},
  pages={
          194-204
        }
}
The environment of a pregnant mother has a life-long impact on later life of offspring. Maternal stress is known to cause low birth weight and programs several physiological dysfunctions in offspring. However, the direct effects of maternal stress on the developing fetus remain largely unknown. The present study focused on the effect of chronic maternal stress on the developmental program and its molecular mechanisms. Pregnant mice were given 6-hour immobilization stress every day from 8.5 days… CONTINUE READING